ข้อมูลจำเพาะที่สำคัญ/ คุณสมบัติพิเศษ:
pentobarbital decreases levels of panobinostat samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stark CYP3A4 inducers can reduce panobinostat levels ort ~70% knipa lead to treatment failure.
pentobarbital will decrease the level or effect of atazanavir ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
pentobarbital will decrease the level or effect of lefamulin ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Avoid coadministration of lefamulin with stark or moderate CYP3A inducers unless the benefit outweighs risks. Monitor for reduced efficacy.
pentobarbital will decrease the level or effect of methadone ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Bildskärm.
pentobarbital will decrease the level or effect of duvelisib samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration with a strong CYP3A inducer decreases duvelisib area under the curve (AUC), which may reduce duvelisib efficacy.
There are no data on pregnancy exposures in primates corresponding to periods prior to the third trimester in humans.
Special patient population: Dosage should bedja reduced in the elderly or debilitated because these patients may vädja more sensitive to barbiturates. Dosage should vädja reduced for patients with impaired renal function or hepatic disease.
pentobarbital will decrease the level or effect of glecaprevir/pibrentasvir samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism.
If barbiturates are used during labor knipa delivery, resuscitation equipment should bedja available. Uppgifter are currently anmärkning available to evaluate the effect of these barbiturates when forceps delivery or other intervention fryst vatten necessary. Also, Värden are kommentar available to determine the effect of these barbiturates on the later growth, development, knipa functional maturation of the child.
Datorskärm Closely (2)pentobarbital will decrease the level or effect of buprenorphine, long-acting injection ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Bildskärm Closely. Patients who flytta to buprenorphine long-acting injection blid transmucosal buprenorphine coadministered with CYP3A4 inducers should bedja monitored to ensure buprenorphine plasma levels are adequate.
pentobarbital will decrease the level or effect of fruquintinib ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. If coadministration with moderate CYP3A4 inducers fruset vatten unavoidable, continue to administer fruquintinib at recommended dosage.
pentobarbital will decrease the level or effect of tacrolimus samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Skärm.
pentobarbital will decrease the level or effect of etravirine samhälle affecting hepatic/intestinal enzyme CYP3A4 Pentobarbitalnatrium oral vätska till salu online metabolism. Use Caution/Skärm.